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Recent advances in peptide engineering have moved beyond the combination of multiple agents, as seen with compounds like tirzepatide, which act on several receptors simultaneously with a single peptide, emulating the effects of combination therapy

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[DOI] [PMC free article] [PubMed] [Google Scholar] 185.Charlier C., Singh N.A., Ryan S.G., Lewis T.B., Reus B.E., Leach R.J., Leppert M